Selected Publications

Cellular Metabolism and Metabolic Regulation

2020

2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer. - Blomme A, Ford CA, Mui E, Patel R, Ntala C, Jamieson LE, Planque M, McGregor GH, Peixoto P, Hervouet E, Nixon C, Salji M, Gaughan L, Markert E, Repiscak P, Sumpton D, Blanco GR, Lilla S, Kamphorst JJ, Graham D, Faulds K, MacKay GM, Fendt S-M, Zanivan S, Leung HY - 2020 - Nat Commun - Pubmed

Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity. - Veys K, Fan Z, Ghobrial M, Bouché A, García-Caballero M, Vriens K, Conchinha NV, Seuwen A, Schlegel F, Gorski T, Crabbé M, Gilardoni P, Ardicoglu R, Schaffenrath J, Casteels C, De Smet G, Smolders I, Van Laere K, Abel ED, Fendt S-M, Schroeter A, Kalucka J, Cantelmo AR, Wälchli T, Keller A, Carmeliet P, De Bock K - 2020 - Circ Res - Pubmed

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. - Boon R, Kumar M, Tricot T, Elia I, Ordovas L, Jacobs F, One J, De Smedt J, Eelen G, Bird M, Roelandt P, Doglioni G, Vriens K, Rossi M, Vazquez MA, Vanwelden T, Chesnais F, El Taghdouini A, Najimi M, Sokal E, Cassiman D, Snoeys J, Monshouwer M, Hu WS, Lange C, Carmeliet P, Fendt SM, Verfaillie CM. - 2020 - Nat Commun. - Pubmed

Stable Isotopes for Tracing Mammalian-Cell Metabolism In Vivo. - Fernández-García J, Altea-Manzano P, Pranzini E, Fendt SM. - 2020 - Trends Biochem Sci. - Pubmed

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism. - Santoro V, Kovalenko I, Vriens K, Christen S, Bernthaler A, Haegebarth A, Fendt SM, Christian S. - 2020 - Oncotarget - Pubmed

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors. - Wang H, Franco F, Tsui YC, Xie X, Trefny MP, Zappasodi R, Mohmood SR, Fernández-García J, Tsai CH, Schulze I, Picard F, Meylan E, Silverstein R, Goldberg I, Fendt SM, Wolchok JD, Merghoub T, Jandus C, Zippelius A, Ho PC. - 2020 - Nat Immunol. - Pubmed

Dynamic ROS Regulation by TIGAR: Balancing Anti-cancer and Pro-metastasis Effects. - Fendt SM, Lunt SY. - 2020 - Cancer Cell - Pubmed

Analyzing the Metabolism of Metastases in Mice. - Altea-Manzano P, Broekaert D, Duarte JAG, Fernández-García J, Planque M, Fendt SM. - 2020 - Methods Mol Biol. - Pubmed

2019

Differentiation but not ALS mutations in FUS rewires motor neuron metabolism. - Vandoorne T, Veys K, Guo W, Sicart A, Vints K, Swijsen A, Moisse M, Eelen G, Gounko NV, Fumagalli L, Fazal R, Germeys C, Quaegebeur A, Fendt S-M, Carmeliet P, Verfaillie C, Van Damme P, Ghesquière B, De Bock K, Van Den Bosch L. - 2019 - Nat Commun. - PubMed

Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells. - Kampen KR, Fancello L, Girardi T, Rinaldi G, Planque M, Sulima SO1, Loayza-Puch F, Verbelen B, Vereecke S, Verbeeck J, Op de Beeck J, Royaert J, Vermeersch P, Cassiman D, Cools J, Agami R, Fiers M, Fendt S-M, De Keersmaecker K. - 2019 - Nat Commun. - PubMed