Selected Publications

Cellular Metabolism and Metabolic Regulation

2020

mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis - Mouna Triki, Gianmarco Rinaldi, Melanie Planque, Dorien Broekaert, Alina M Winkelkotte, Carina R Maier, Sudha Janaki Raman, Anke Vandekeere, Joke Van Elsen, Martin F Orth, Thomas G P Grünewald, Almut Schulze, Sarah-Maria Fendt - 2020 - Cell Rep - Pubmed

Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization - Jing Zhang, Jonathan Muri, Gillian Fitzgerald, Tatiane Gorski, Roberto Gianni-Barrera, Evi Masschelein, Gommaar D’Hulst, Paola Gilardoni, Guillermo Turiel, Zheng Fan, Tong Tong Wang, Mélanie Planque, Peter Carmeliet, Luc Pellerin, Christian Wolfrum, Sarah-Maria Fendt, Andrea Banfi, Christian Stockmann, Inés Soro-Arnáiz, Manfred Kopf, Katrien De Bock - 2020 - Cell Metabolism - Pubmed

Glutamine Metabolism Controls Chondrocyte Identity and Function - Steve Stegen, Gianmarco Rinaldi, Shauni Loopmans, Ingrid Stockmans, Karen Moermans, Bernard Thienpont, Sarah-Maria Fendt, Peter Carmeliet, Geert Carmeliet - 2020 - Developmental Cell - Pubmed

2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer. - Blomme A, Ford CA, Mui E, Patel R, Ntala C, Jamieson LE, Planque M, McGregor GH, Peixoto P, Hervouet E, Nixon C, Salji M, Gaughan L, Markert E, Repiscak P, Sumpton D, Blanco GR, Lilla S, Kamphorst JJ, Graham D, Faulds K, MacKay GM, Fendt S-M, Zanivan S, Leung HY - 2020 - Nat Commun - Pubmed

Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity. - Veys K, Fan Z, Ghobrial M, Bouché A, García-Caballero M, Vriens K, Conchinha NV, Seuwen A, Schlegel F, Gorski T, Crabbé M, Gilardoni P, Ardicoglu R, Schaffenrath J, Casteels C, De Smet G, Smolders I, Van Laere K, Abel ED, Fendt S-M, Schroeter A, Kalucka J, Cantelmo AR, Wälchli T, Keller A, Carmeliet P, De Bock K - 2020 - Circ Res - Pubmed

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. - Boon R, Kumar M, Tricot T, Elia I, Ordovas L, Jacobs F, One J, De Smedt J, Eelen G, Bird M, Roelandt P, Doglioni G, Vriens K, Rossi M, Vazquez MA, Vanwelden T, Chesnais F, El Taghdouini A, Najimi M, Sokal E, Cassiman D, Snoeys J, Monshouwer M, Hu WS, Lange C, Carmeliet P, Fendt SM, Verfaillie CM. - 2020 - Nat Commun. - Pubmed

Stable Isotopes for Tracing Mammalian-Cell Metabolism In Vivo. - Fernández-García J, Altea-Manzano P, Pranzini E, Fendt SM. - 2020 - Trends Biochem Sci. - Pubmed

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism. - Santoro V, Kovalenko I, Vriens K, Christen S, Bernthaler A, Haegebarth A, Fendt SM, Christian S. - 2020 - Oncotarget - Pubmed

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors. - Wang H, Franco F, Tsui YC, Xie X, Trefny MP, Zappasodi R, Mohmood SR, Fernández-García J, Tsai CH, Schulze I, Picard F, Meylan E, Silverstein R, Goldberg I, Fendt SM, Wolchok JD, Merghoub T, Jandus C, Zippelius A, Ho PC. - 2020 - Nat Immunol. - Pubmed

Dynamic ROS Regulation by TIGAR: Balancing Anti-cancer and Pro-metastasis Effects. - Fendt SM, Lunt SY. - 2020 - Cancer Cell - Pubmed