Selected Publications

Growth Control and Cancer Research

2019

Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. - Moya IM, Castaldo SA, Van den Mooter L, Soheily S, Sansores-Garcia L, Jacobs J, Mannaerts I, Xie J, Verboven E, Hillen H, Algueró-Nadal A, Karaman R, Van Haele M, Kowalczyk W, De Waegeneer M, Verhulst S, Karras P, van Huffel L, Zender L, Marine JC, Roskams T, Johnson R, Aerts S, van Grunsven LA, Halder G. - 2019 - Science - PubMed

2018

Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine. - Moya IM, Halder G. - 2018 - Nat Rev Mol Cell Biol - PubMed

Modulation of the Hippo pathway and organ growth by RNA processing proteins. - Mach J, Atkins M, Gajewski KM, Mottier-Pavie V, Sansores-Garcia L, Xie J, Mills RAndrew, Kowalczyk W, Van Huffel L, Mills GB, Halder G. - 2018 - Proc Natl Acad Sci U S A - PubMed

The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models. - Vicente C, Stirparo R, Demeyer S, de Bock CE, Gielen O, Atkins M, Yan J, Halder G, Hassan BA, Cools J. - 2018 - J Hematol Oncol - PubMed

The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes. - Jacobs J, Atkins M, Davie K, Imrichova H, Romanelli L, Christiaens V, Hulselmans G, Potier D, Wouters J, Taskiran II, Paciello G, González-Blas CB, Koldere D, Aibar S, Halder G, Aerts S. - 2018 - Nat Genet. - PubMed

Cell Junctions in Hippo Signaling. - Karaman R, Halder G. - 2018 - Cold Spring Harb Perspect Biol - PubMed

2017

Hippo Reprograms the Transcriptional Response to Ras Signaling. - Pascual J, Jacobs J, Sansores-Garcia L, Natarajan M, Zeitlinger J, Aerts S, Halder G, Hamaratoglu F. - 2017 - Dev Cell - PubMed

2016

An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model. - Atkins M, Potier D, Romanelli L, Jacobs J, Mach J, Hamaratoglu F, Aerts S, Halder G. - 2016 - Curr Biol - PubMed

The Hippo pathway in cellular reprogramming and regeneration of different organs. - Moya IM, Halder G. - 2016 - Curr Opin Cell Biol - PubMed

2015

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. - Meng Z, Moroishi T, Mottier-Pavie V, Plouffe SW, Hansen CG, Hong AW, Park HWoo, Mo J-S, Lu W, Lu S, Flores F, Yu F-X, Halder G, Guan K-L. - 2015 - Nat Commun - PubMed