Full Professor of Medicine, Dept. of Human Genetics, KU Leuven
Group Leader, VIB-KU Leuven Center for Cancer Biology (CCB)
Science Director, VIB-KU Leuven CCB
Prof. Diether Lambrechts was trained as an engineer at KU Leuven and worked under P. Carmeliet on the role of vascular endothelial growth factor in amyotrophic lateral sclerosis for his PhD and postdoc until 2007. He then worked at the Wellcome Trust Centre for Human Genetics in the Nuffield Department of Clinical Medicine at the University of Oxford, England, before joining VIB as an independent VIB group leader. His research group, the Laboratory of Translational Genetics at the VIB Center for Cancer Biology in KU Leuven, is focused on tackling important questions in oncology by translating genome-scale data sets into clinically applicable knowledge. Investigations are based on the application of cutting-edge genome sequencing technologies and advanced bioinformatics, and on the seamless integration of genomic data sets with clinical and fundamental biological information to generate novel insights and useful biomarkers for the field of oncology. His research has resulted so far to 117 high-impact factor journals (IF>10, H-index = 73), several successful grant applications (ERC consolidator grant, H2020, etc.), 13 patents and several scientific awards/prices (eg. the Karel-Lodewijk Award for Human Medicine, the Galenus Prize for Pharmacology, the AstraZeneca Award for Translational Research and the Agilent Thought Leader Award). In 2018, he was recognized by Clarivate as a highly-cited scientist. Moreover, he succeeded in translating his research into clinically meaningful findings, eg. IdyllaTM MSI test (CE IVD) from Biocartis NV to detect microsatellite instability in cancer tissue sections. Since 2015, Diether is director of the VIB Center for Cancer of Biology.