Comment article in Nature Reviews Immunology by L.A Teuwen, V. Geldhof, A. Pasut & P. Carmeliet
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COVID-19: the vasculature unleashed
On the basis of emerging evidence from patients with COVID-19, we postulate that endothelial cells are essential contributors to the initiation and propagation of severe COVID-19. Here, we discuss current insights into the link between endothelial cells, viral infection and inflammatory changes and propose novel therapeutic strategies.