Selected Publications

Tumor Microenvironment and Therapeutic Resistance

2019

Regulation of Blood and Lymphatic Vessels by Immune Cells in Tumors and Metastasis. - Mazzone, M, and Bergers G - 2019 - Annu Rev Physio - Pubmed

Peptide-guided nanoparticles for glioblastoma targeting - Säälik P, Lingasamy P, Toome K, Mastandrea I, Rousso-Noori L, Tobi A, Simon-Gracia L, Hunt H, Paiste P, Kotamraju VR, Bergers G, Asser T, Rätsep T, Ruoslahti E, Bjerkvig R, Friedmann-Morvinski D, Teesalu T - 2019 - Journal of Controlled Release - Pubmed

IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo. - Harris AJ, Mirchandani AS, Lynch RW, Murphy F, Delaney L, Small D, Coelho P, Watts ER, Sadiku P, Griffith D, Dickinson RS, Clark E, Willson JA, Morrison T, Mazzone M, Carmeliet P, Ghesquiere B, O'Kane C, McAuley D, Jenkins SJ, Whyte MKB, Walmsley SR. - 2019 - Am J Respir Crit Care Med - P

Tumors versus chronic wounds: an immune cell's perspective. - Hua, Y and Bergers, G - 2019 - Frontiers in Immunology - Pubmed

2018

A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma - Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM - 2018 - Nature Cell Biology - Pubmed

Vascular targeting of LIGHT normalizes blood vessels in primary brain cancer and induces intratumoural high endothelial venules - He, B., Jabouille, A., Steri, V., Johansson-Percival, A., Michael, I.P., Kotamraju, V.R., Junckerstorff, R., Nowak, A.K., Hamzah, J., Lee, G., Bergers, G., and Ganss, R. - 2018 - Journal of Pathology - Pubmed

The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer - Missiaen R, Mazzone M, and Bergers G - 2018 - Seminars in Cancer Biology - Pubmed

Where have all the T-cells gone? - Vella, G. and Bergers, G. - 2018 - Immunity - Pubmed

2017

Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation - Allen E, Jabouille A, Rivera LB, Lodewijckx I, Missiaen R, Steri V, Feyen K, Tawney J, Hanahan D, Michael IP & Bergers G - 2017 - Science Translational Medicine - Pubmed

Cross-activating c-Met/beta 1 integrin complex drives metastasis and invasive resistance in cancer - Jahangiri, A., Nguyen, A., Chandra, A., Sidorov, M.K., Yagnik, G., Rick, J., Han, S.W., Chen, W., Flanigan, P.M., Schneidman-Duhovny, D., Mascharak, S., De Lay, M., Imber, B., Park, C.C., Matsumoto, K., Lu, K., Bergers, G., Sali, A., Weiss, W.A., and Aghi, M.K. - 2017 - Proc Natl Acad Sci U S A - Pubmed